Learn Index · Living Things and the Human Body Grade 6–8

Human body systems and how they work together

The immune, endocrine, excretory and other systems work with the circulatory and nervous systems to keep the body healthy.

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A team of systems

Your body has about eleven organ systems. Each has its own job, but none works alone. They constantly communicate and depend on each other to keep you alive.

The major systems

System Main organs Main job
Skeletal Bones, cartilage Support, protection, blood cell production
Muscular Skeletal, cardiac, smooth muscle Movement
Circulatory Heart, blood vessels, blood Transport oxygen, nutrients, wastes
Respiratory Lungs, trachea, diaphragm Gas exchange
Digestive Stomach, intestines, liver Break down and absorb food
Nervous system Brain, spinal cord, nerves Fast control and communication
Endocrine system Pituitary, thyroid, pancreas, adrenal glands Slow control using hormones
Excretory system Kidneys, bladder Remove wastes; balance water
Immune system White blood cells, lymph nodes, spleen Fight infection
Integumentary Skin, hair, nails Protection, temperature control
Reproductive Ovaries, testes Produce offspring

Two control systems

The body has two ways of sending messages:

Nervous system Endocrine system
Messenger Electrical impulses along nerves Hormones in the blood
Speed Very fast (milliseconds) Slower (seconds to hours)
Effect lasts Briefly Longer
Example Pulling your hand from a hot stove Growth hormone controlling height

Homeostasis

Homeostasis is keeping internal conditions stable, even when the outside world changes. Systems work together to control:

  • Body temperature (about 37 °C)
  • Blood sugar
  • Water balance
  • Oxygen and carbon dioxide levels

Example: When you get too hot, your nervous system detects it. Your skin makes sweat, and blood vessels near the skin widen to release heat. When you’re cold, you shiver (muscles make heat) and blood vessels narrow.

How systems work together

Getting oxygen to cells

  1. The respiratory system takes in oxygen; gas exchange happens in tiny air sacs called alveoli.
  2. The circulatory system carries oxygen in red blood cells.
  3. Cells use oxygen to release energy from food.
  4. Carbon dioxide travels back to the lungs to be breathed out.

Using food

  1. The digestive system breaks food into nutrients like glucose.
  2. Nutrients enter the blood through the small intestine.
  3. The circulatory system delivers them to cells.
  4. The pancreas (endocrine system) releases insulin to help cells take in glucose.
  5. The excretory system removes wastes such as urea through the kidneys.

Fight or flight

When you’re frightened:

  • the nervous system signals the adrenal glands
  • they release the hormone adrenaline
  • your heart beats faster and you breathe faster
  • more blood flows to your muscles so you can react quickly

Fighting disease

The immune system defends the body:

  • First line: skin, mucus and stomach acid block germs.
  • Second line: white blood cells attack invaders and cause inflammation.
  • Third line: specific defences make antibodies and remember germs, so you fight them faster next time. Vaccines train this memory.

When systems fail

Diseases often affect more than one system. Diabetes is an endocrine problem (not enough insulin, or cells don’t respond to it), but it can damage the circulatory system, kidneys, eyes and nerves.

Common mistakes

  • Thinking the heart’s only job is pumping. It depends on nervous signals and hormones to change speed.
  • Mixing up excretion and digestion. Digestion breaks down food; excretion removes wastes made by cells.

Try it yourself

Choose an activity, such as running a race, eating a sandwich or getting a cold. List at least four systems involved and explain what each one does.

Quick recap

  • The body has about eleven organ systems that depend on each other.
  • The nervous system sends fast signals; the endocrine system uses slower hormones.
  • Homeostasis keeps temperature, blood sugar and water levels stable.
  • Respiratory and circulatory systems work together to deliver oxygen.
  • The immune system defends the body in three lines.